Thursday, October 17, 2019
Business Technology Essay Example | Topics and Well Written Essays - 750 words
Business Technology - Essay Example It actually enhances the communication process between people and the organizations. Despite the advantages, several demerits and disadvantages of the application of advanced technology in the business process affects the relationship between an individual and his or her particular organizations, such as bank, school or shops. Several business organizations and banks are implementing online transaction system in the business processes to bring efficiency in the payment making process. People are still trying to avoid this online payment process due to the threat of account hacking by cyber thieves or theft of privacy or personal relationship. In terms of social relationship between friends and families, lack of security in several social media networking sites allow people to access the accounts of different users. These issues generally affect the social and business relationship of people. It is clear from above discussions that the introduction and implementation of technology in daily operations have several advantages as well as disadvantages. Online shopping, online order placing, online distribution, online application and e-CRM are the several advantages of the implementation of advanced technology in the business operation process. In addition to this, emergence of several social media networking sites help people to maintain effective relationship with the friends, families, colleagues and several business organizations (Sternheimer, 2013). But, issues like, online hacking and theft of privacy is affecting the relationship between the people and their respective organizations. It is important for both the users of technological equipments or applications and the organizations to maintain efficiency in the adoption and... This essay approves that several demerits and disadvantages of the application of advanced technology in the business process affects the relationship between an individual and his or her particular organizations, such as bank, school or shops. Several business organizations and banks are implementing online transaction system in the business processes to bring efficiency in the payment making process. People are still trying to avoid this online payment process due to the threat of account hacking by cyber thieves or theft of privacy or personal relationship. In terms of social relationship between friends and families, lack of security in several social media networking sites allow people to access the accounts of different users. These issues generally affect the social and business relationship of people. It is clear from above discussions that the introduction and implementation of technology in daily operations have several advantages as well as disadvantages. Online shopping, online order placing, online distribution, online application and e-CRM are the several advantages of the implementation of advanced technology in the business operation process. This paper makes a conclusion that organizations are using advanced technology in the business processes in order to maintain strong relationship with the target customers. Despite the advantages, people can face several through these online business or social applications.
The Role of a PPC Manager in a Leading Company Term Paper
The Role of a PPC Manager in a Leading Company - Term Paper Example Goals could be varied for clients. For some clients, the aim is branding and for some others, it could be a direct response. Some clients focus on improving their return on investment and some others focus on improving the traffic to their website. The role of the PPC Manager also involves identifying the goals of the clients, setting up, and maintaining the campaign in such a way that the aim of the client is fulfilled. Based on job analysis, the key aspects of the role include managing a portfolio of client accounts, interacting directly with the clients to understand their business, driving revenue and improving customer satisfaction. The PPC Manager should be able to optimize the performance of the campaign, set and implement strategies to achieve the goal of the client and demonstrate product expertise on PPC models. Apart from being an expert on analytics and reporting, they should also demonstrate their expertise on industry trends and customer education. Ã The basic pre-requisite of the candidate is to have around 3 years of experience in key account management, have proficiency in Microsoft Excel, be flexible and open, have very good communication and interpersonal skills. The candidate also should be a graduate with a good academic background. The HR Executive would conduct the phone screen interview. The aim of this interview is to see if the candidate fulfills the basic criterion required for the job.Ã
Wednesday, October 16, 2019
Business Technology Essay Example | Topics and Well Written Essays - 750 words
Business Technology - Essay Example It actually enhances the communication process between people and the organizations. Despite the advantages, several demerits and disadvantages of the application of advanced technology in the business process affects the relationship between an individual and his or her particular organizations, such as bank, school or shops. Several business organizations and banks are implementing online transaction system in the business processes to bring efficiency in the payment making process. People are still trying to avoid this online payment process due to the threat of account hacking by cyber thieves or theft of privacy or personal relationship. In terms of social relationship between friends and families, lack of security in several social media networking sites allow people to access the accounts of different users. These issues generally affect the social and business relationship of people. It is clear from above discussions that the introduction and implementation of technology in daily operations have several advantages as well as disadvantages. Online shopping, online order placing, online distribution, online application and e-CRM are the several advantages of the implementation of advanced technology in the business operation process. In addition to this, emergence of several social media networking sites help people to maintain effective relationship with the friends, families, colleagues and several business organizations (Sternheimer, 2013). But, issues like, online hacking and theft of privacy is affecting the relationship between the people and their respective organizations. It is important for both the users of technological equipments or applications and the organizations to maintain efficiency in the adoption and... This essay approves that several demerits and disadvantages of the application of advanced technology in the business process affects the relationship between an individual and his or her particular organizations, such as bank, school or shops. Several business organizations and banks are implementing online transaction system in the business processes to bring efficiency in the payment making process. People are still trying to avoid this online payment process due to the threat of account hacking by cyber thieves or theft of privacy or personal relationship. In terms of social relationship between friends and families, lack of security in several social media networking sites allow people to access the accounts of different users. These issues generally affect the social and business relationship of people. It is clear from above discussions that the introduction and implementation of technology in daily operations have several advantages as well as disadvantages. Online shopping, online order placing, online distribution, online application and e-CRM are the several advantages of the implementation of advanced technology in the business operation process. This paper makes a conclusion that organizations are using advanced technology in the business processes in order to maintain strong relationship with the target customers. Despite the advantages, people can face several through these online business or social applications.
Tuesday, October 15, 2019
Research paper SarbanesOxley Act of 2002 and DoddFrank law on banking Essay
Research paper SarbanesOxley Act of 2002 and DoddFrank law on banking industry - Essay Example It encouraged full disclosure of information to enable citizens to evaluate the worth of the firm before investing in it. The Dodd-Frank law also seeks to tighten regulation on credit rating agencies (Simon, 1989). Whether this was achieved or not has been a subject of debate around many corners. To assess the effects of the legislation, this paper will look at the wealth effects that surround the passage of the Act. The investors and the analysts will assess the benefits that this act has brought to their wealth status and whether or not it brought a significant difference since its enacting. If they determine that there are changes due to act and that the act is having positive effects in the investment business then they will assess it positively if otherwise they will give it a negative assessment. However, for the purposes of research, this paper will assume that the share prices of the firms that were expected to incur greater costs during compliance were negatively affected by the Act. This is because their share prices fell and it has been a challenge to bring them up. The paper will assume this position following the hype that followed the enactment of the Act especially in the media. The media popularized the negative effects of this legislation to the share prices of firms (Bloomfield, 2005). To assess the effects of this legislation, the paper will consider several studies that focus on the financial impacts brought about by disclosure of financial information then engage in an independent discussion on the same (DeFond, 2004). Previous studies indicate that financial disclosure by firms is very important to the shareholders. The shareholders need this kind of information in order to make decisions on which stocks they would invest in. It also helps the analyst by giving them the facts they can use in advising their clients. Being open to the public also helps the firm well manage its expectations. However, how the disclosure impacts on the
Social grade Essay Example for Free
Social grade Essay After analysing my market research, I have concluded that the social grade of the local area is (B) Lower Management, and the average pay is betweenà 25000 and 35000. The majority of the people do shop locally, the main reason being that the local shops cater for their needs. This shows that there would be a place for me in this local area because there arent any specialised Internet cafes, aimed at social group B. The majority of people surveyed fit into this group, so it makes sense to primarily aim for them, and then the skilled non-manual workers. Planning restrictions Planning restrictions are used to restrict where a business can build or start up. If the government rejects then it would be against the law for the company to build there. Planning restrictions help to protect beautiful nature from being destroyed. They also stop factories from opening near homes. Planning restrictions also help bring businesses into areas where there is high unemployment. From research into local planning restrictions, I have found out that I must get permission for any ballads placed by me near my shop, shutters, extra building at the rear of shop and any structural work. I do not need to worry about the replacement of doors and windows, as my business is a non-listed building. Social effects of my shop Social costs are the costs that the rest of the area must pay because of where a business or factory is situated. There can also be social benefits which means what is gained by the local area from placing a business there. The social costs as a result of where I place my business are increase in litter and my result in local competition closing down. The social benefits from placing my business are that people shop locally, creates one or two extra jobs and helps the local economy. Evaluation The place that I have chosen has more advantages than disadvantages. This is because my shop will be right next to a main road which will allow people to see any promotions, and they will be drawn to the area by a Sainsburys Local. There is also a bus stop a few metres away from my shop which will make it easy to get to my shop. Another major advantage is that there is a bank nearby that has a cash point meaning it is easy to withdraw cash. There is also a college very near to my internet so there is a good chance students will come and chat with friends etc. However, the disadvantage is that there are likely to be computers in the college so it would be more likely they would use it rather than paying for the use of a computer and internet. There are some disadvantages; primarily, there is no dedicated car park, and there are parking restrictions. The main parking restrictions are that there is no parking on certain points between 6pm and 8pm Monday-Friday. The planning restrictions in the local area are not very strict so this will help if I want to make changes to my, business. There are more benefits than costs, the only ones being litter and closing of competition. The major benefit of me placing my shop in the chosen area is that there would be a good chance of more people coming into the local area that would help other local shops. How will I set the price? The price must be right, as people will have to buy large numbers to make profit. The price you charge depends on what you are trying to do. I am selling pastries, tea, coffee etc as well as providing an internet service so I will have a low prices in order to attract a lot of customers and to see if my business will succeed. It is different for me as I dont sell things (apart from pastries, coffee, tea etc) to make a profit; I provide a computer service as my main way of making a profit. My price My price will be as low as possible, so that I can attract the largest amount of customers. I will also have some goods such as pastries, coffee; tea etc at is at high prices because they are unique. I am aiming at social group B. How to price? This is very important, as I must decide how to price the use of the Internet and how to price the food and drinks. Hour based pricing will be the most suitable way to charge the use of the computer and the Internet. The food and drinks will be charged at high price seeing that the social grade of this local area is group B and most of the local area earn i 25000+ so they will be more likely to spend more money. From my first plan, I know my place, my pricing structure and what group I am targeting. After evaluating my first action plan, I have found that I need to cover areas that I missed in my previous plan. . I will be selling food and drink, so each and every product must have a good strong brand that makes it recognisable to people. A very strong brand is Coke a Cola brand, As the colours, shape of cans, and lettering tell the buyer what the product is. The characteristics of the brand come from the products physical features of the product. This means the taste and the shape of the product. The manufacturer through adverts and packaging creates these. What is the aim of advertising? The aims of advertising are to inform people about the Internet cafi , create an image, increase sales, compete with other shops and introduce new products into the market. The aims of my advertising will be to increase sales, compete with other shops and to create an image. Informative advertising Currently, the biggest spender on this form of advertising is the government. This advertising is used to pass on information to the public. The passing on of this information is very important in any advert. Persuasive advertising Their adverts try to persuade the viewer that their products are much better then the competition. Their goal is to attract people to buy their products. There are different types of pervasive advertising. They could be adverts that show a famous person using the product or adverts that compare one product with another. Public relations Public relations are the department that tries to promote the company and shows the good side of the company to the public. Advertising agencies Advertising is a very expensive business; to make sure that the money is well spent they will hire a company to do it right. For an advertising campaign to be successful it must reach the right audience, be attractive and appealing and make the money that the audience cost back in sales. Control over advertising In an advert you cant just put anything in it, there are certain rules. There is a code of practice inside the advertising industry that you must obey. The trade description act, which means that the advert must mean what it, says. I plan to use informative advertising, as I want to inform people of the benefits of buying from my shop. What types of media are there for advertising? There are many different types of advertising, each has advantages, and disadvantages: Television This is a very powerful media to use to get your message across. The advert that is produced will be seen by millions. The time at which your advert is shown effects who see it. If your product is for children then you would show your advert during childrens programmes. You must also take into account the number of people watching, as this will effect the cost. To produce an advert you must take into consideration how many adverts can you afford, as there would be no point in only being able to run your advert once and when will it be shown and is the advert its self correct? The advantages are that television reaches a large audience throughout the country and the adverts can make the product look much better than in print. The disadvantages are that it is extremely expensive. Radio This method of advertising is very similar as television adverting, but it is cheaper and sound is used instead of visual images. In a radio advert a theme tune is used. The disadvantages are that people may switch station when the advert comes on, if there is poor reception then the listener may miss the advert. The advantages are cheaper than television, large audiences can be reached, this type of advertising is very good for local shops and the advert can be repeated many times.
Sunday, October 13, 2019
Minimizing Cost of Volatile Inhalational Anesthetics
Minimizing Cost of Volatile Inhalational Anesthetics P The population that will be examined are male and female patients with a physical status (PS) of I-II requiring general anesthesia for surgery, ages 20-40. I The intervention being introduced is utilizing Sevoflurane (UltaneÃâà ®) as the inhaled anesthetic for surgeries requiring general anesthesia lasting less than one hour. C The comparison group will be those utilizing Desflurane (SupraneÃâà ®) as the inhaled anesthetic for surgeries requiring general anesthesia lasting less than one hour. O The use of Sevoflurane for surgery cases requiring general anesthesia for less than one hour will save money for the anesthesia department rather than using Desflurane. PICO Question: Will the use of Sevoflurane rather than Desflurane in surgeries requiring general anesthesia lasting less than one hour save money for the anesthesia department? Abstract Inhalation anesthetics are used millions of times every single day in surgeries requiring general anesthesia all over the world. Cost containment is anesthesia is no longer an option, it is an absolute necessity. Anesthetic drugs account for up to 6 percent of total hospital pharmacy costs and inhalation agents comprise over twenty percent of that as a whole. One of the areas most amenable to cost reduction in the anesthesia department budget is the use and choice of inhalational anesthetic. A quantitative quasi-experimental controlled trial was developed to determine if money could be saved in the anesthesia department by utilizing Sevoflurane as the inhalational anesthetic for surgeries requiring general anesthesia less than one hour rather than Desflurane. The study chose males and females, ages twenty to forty, requiring general anesthesia at a mid-sized, urban, teaching hospital in South-Western Pennsylvania. Prices of anesthetic agents were gathered from the same facility and c alculated to determine the total cost savings that would ensue with the use of the interventional inhalation agent rather than that used by the control group. The use of Sevoflurane for two-thirds of the cases which Desflurane was used saved the institution over twenty thousand dollars. Key Words: Inhalational Anesthetics, Pharmacoeconomics, Desflurane, Sevoflurane, Anesthesia Introduction Research Problem: The cost of health services and technologies continue to increase exponentially while resources are finite. Developing effective strategies to minimize costs without compromising patient safety and quality of care are the most difficult challenges medical professionals experience.13 Inhalational anesthetics comprise twenty percent of the drug expenses in anesthesia departments. The cost of inhalational anesthetics depend on their potency, which is their minimum alveolar concentration (MAC), the minimum amount of inhalational anesthetic needed in the lungs to facilitate the absence of movement to noxious stimuli, the fresh gas flows (FGF) used to deliver the anesthetic gas, the amount of anesthetic vapor released by each milliliter of liquid, and the price of the inhalational anesthetics themselves.2,16 Inhalational anesthetics are used when general anesthesia is needed for surgery and patients do not have diseases or conditions which would preclude them from being able to utilize them (e.g. those who have malignant hyperthermia). The anesthesia provider decides which inhalational anesthetic is best for a given patient, based on their history and needs for the surgery. The problem exists when providers just use whichever anesthetic is most easily accessible at that time without minding any consideration as to the cost of the particular gas and the level of FGF they are using, which is purely a waste of money as the patient will lose heat and humidity, waste high levels of inhaled anesthetic, and demise cost containment for the anesthesia department. Statement of Purpose The purpose of this research study is to determine whether the implementation of Sevoflurane as the choice inhalation anesthetic for surgery requiring general anesthesia for procedures lasting less than one hour rather than using Desflurane will provide cost containment for the anesthesia department. Objectives/Aims The objective of this study is to provide an avenue of cost containment for the anesthesia department of a mid-sized, urban, teaching hospital and overall savings for the medical health system. This will allot more money in the department budget to be spent on technological advances, and equipment used to better develop opportunities for patient safety, the ultimate goal of all medical professionals. Review of Literature: Many studies explore different methods of cost containment in the anesthesia department. Almost all of the studies exclusively develop the notion of cost savings related to the fresh gas flows used to deliver inhalation anesthetics. Cost containment requires primarily a decrease in FGFs, but it may also be influenced by a rational use of the available halogenated agents.3 With the advances in technology and the ultra-modern anesthesia machines available, anesthesia providers should feel safe in using minimal FGFs to deliver anesthesia that would not harm their patients in any way.3 Anesthetists can directly influence healthcare costs through the patterns in which they practice, which includes reducing the FGFs chosen during inhalational anesthesia, which will directly affect the amount of inhaled anesthetic delivered to the patient and ultimately the costs which are attributable to inhaled anesthetics.10,15 Depending on breathing systems used, which are mostly semi-open today, up to ninety percent of the anesthetic gases delivered escapes into the atmosphere completely unused. By using low-flow anesthesia, most of the patients air they exhale is recycled and then returned to the patients lungs after the carbon dioxide from the exhaled air has been absorbed.15 There are also advantages of using low-flow anesthesia such as conserving the patients heat and humidity, making it less of a need to warm the patient externally, which will cut down costs on heating blankets and the like, as well as maximized the rebreathing of the exhaled anesthetic, which will cut down on the amount of gas vented into the environment,6 but there are cautions that anesthesia providers must take when using low FGFs, as titration in inhalation anesthetic is not as easily predicted. Product labeling for Sevoflurane does include a warning that patient exposure should not exceed two hours using FGF rates greater than one and less than two liters per minute.7 Also, it is not recommended at all to maintain FGFs less than one when using Sevoflurane as the patients inhalational anesthetic of choice. These recommendations are to minimize the risk of exposure of the patient to compound A which in laboratory animals, has been shown to be linked to nephrotoxicity. There are no minimum flow rate designations that exist for Desflurane.7,8 Isoflurane is less expensive than Sevoflurane and Desflurane at equal dose and the same FGFs.7 When comparing Sevoflurane with Desflurane as they are being used for surgeries lasting less than two hours, there was a ninety percent decrement time for Sevoflurane which approached the short duration of anesthesia matching that of Desflurane. However, when the duration of anesthesia increased over two hours, Sevofluranes ninety percent decrement time approached that of Isoflurane.7 The cost of inhaled anesthetic agent can be estimated by using an equation that provides the cost of anesthetic per MAC hour: Cost per MAC hour ($) = [(Conc.)(FGF rate)(Duration)(MW)(Cost per mL)] / [(2412)(D)]6 The cost of one milliliter of Isoflurane is twenty-three cents, Sevoflurane is forty-one cents, and Desflurane is eighty-three cents. Regardless of the fast onset and emergence Desflurane offers, the cost of administering Desflurane is greater than the cost of Sevoflurane at any FGF rate.10,11 The cost of inhaled anesthetic agent can be estimated by calculating the cost per MAC hour, which is the administration of inhaled anesthetic agent at 1 MAC for a one hour time interval. The cost can be calculated using the concentration percent on the anesthetic dial of gas delivered, the FGF rate chosen, the duration of the anesthetic (sixty minutes in this case), the molecular weight of the anesthetic agent (MW in grams), cost per mL of liquid agent (in dollars), a factor accounting for the molar volume of a gas at twenty-one degrees Celsius (a constant of two thousand four-hundred twelve), and the density of the agent (D in grams/mL). Cost per MAC hour ($) = [(Conc.)(FGF rate)(Duration)(MW)(Cost per mL)] / [(2412)(D)]6 The cost per MAC hour can be seen in Table 2. Desflurane is associated with a shorter recovery as is Sevoflurane, but the differences between the two in terms of patient discharge cannot be consistently shown in research studies.13 Gupta evaluated n=246 patients for recovery time after undergoing surgeries less than two hours with either Sevoflurane or Desflurane. Patients given Desflurane were able to open their eyes sixty seconds before those who received Sevoflurane, P When comparing Sevoflurane and Isoflurane for patients who are undergoing surgery for more than two hours, Gupta evaluated n=634 patients. The patients who underwent Sevoflurane were able to open their eyes sooner, P Savings of more than one hundred thousand dollars resulted from the change of using Desflurane to using Sevoflurane in the operating rooms at Montefiore Medical Center in the Bronx, New York. Traynor noted that three bottles of Desflurane are needed to maintain a level of anesthesia equal to that of one bottle of Sevoflurane, making this agent much less expensive for the hospital to utilize, with no difference in patient discharge times. Reviews of Literature indicated that patients who received Desflurane could be extubated in the operating room about two minutes sooner than the patients who received Sevoflurane; an advantage seen meaningless in the large scale of the operating room sequences.9,15 Methodology The research design chosen was a quasi-experimental study. It involved the use of an experimental group and a control group. It is important to mention that the control group was compiled from hospital anesthesia records. The study did not involve randomization as a medical facilitys computer database cannot throughput this information. Permission from a mid-sized, Southwestern Pennsylvania teaching hospital was granted and all information gathered from the facility involved no patient identifiers, including gender or age. The hospitals Institutional Review Board (IRB) was provided all details of the research study and deemed the research experiment to be exempt and permission was granted to start the study without any changes in the studys design. General anesthesia data spreadsheets were gathered from the hospital exemplifying a patient anesthesia case total for the month of July, 2012. From this information, it was determined there were a total of n0=1,459 general anesthesia cases and after careful analysis, it was found that n1=500 cases lasted less than one hour and n2=959 cases lasted equal to or more than one hour in length from the beginning of anesthesia delivery to the end of the surgical procedure, as seen in Chart 1 in Appendix A. The Southwestern Pennsylvania hospital was asked to provide their costs for Desflurane, Sevoflurane, and Isoflurane inhalation anesthetics. These prices can be seen in Table 1 of Appendix A. Utilizing the equation to calculate the amount of inhaled anesthetic used during a general surgical case in a sixty minute time duration, MAC hour costs could be calculated as seen in Table 3. The pharmacy was also asked to provide how many bottles of inhalational anesthetic are bought and used annually in their operating rooms. These results are seen in Chart 2 and calculated annual costs of the anesthetics are shown in Chart 3 in Appendix C The experimental group for the research procedure involved men and women, ages twenty to forty, with PS scores of I and II, who were undergoing general anesthesia for surgery cases lasting less than one hour. These patients were administered Sevoflurane as their inhalational anesthetic during surgery at a FGF rate of 2 liters per minute (LPM). To be sure all patients were given the same standard induction regimen, all drug doses were based on current body weight calculations. Propofol, a sedative hypnotic was given at 2 milligrams per kilogram (mg/kg). Fentanyl, an opioid analgesic was given at 5 micrograms per kilogram (mcg/kg). Midazolam, a benzodiazepine sedative was given at a standard dose of 2mg/kg. Lidocaine, a class 2 anti-arrhythmic agent was given at 1.5 mg/kg. All patients participating in the study were given their induction medications at these doses provided. In the preoperative area, all patients were given the right to participate or not participate in the research experiment as they were provided a letter of informed consent, which described completely that they would be treated no differently than any other patient and they were voluntarily consenting to participate in a research study as an individual, and in no way obligated to participate if they were unwilling to do so. Those who were not involved in the experimentation are those patients who were unwilling to consent to participate in the experiment as an individual. Those with malignant hyperthermia were excluded from the study as they could not receive volatile inhalational anesthetics. Patients who required additional narcotic for pain during surgery were excused from participation. Those with chronic kidney disease or kidney failure were also not involved in the experiment as Sevoflurane, the experimental variable could lead to kidney complications. Participants who only were given inhalational anesthetic for painful stimulation during intravenous sedation were also excluded from participation in this study. It was important to determine which inhalational anesthetic was favored most by anesthesia providers at the Southwestern Pennsylvania hospital between Sevoflurane and Desflurane for general anesthesia cases lasting less than one hour. Surveys were sent out to all members of the anesthesia team as titled Survey 1 in Appendix D. Ethics/Professionalism Ethical considerations were regarded during the completion of the study from start to finish. All information gathered from a Southwestern Pennsylvania hospital was kept in confidence and destroyed at the finish of the study by professional paper shredding services. Participant names, ages, race, nationality, and medical histories were not gathered from the hospital and were blinded from the investigator, owing to complete confidence of all those who participated during a twelve month interval. Results Results are pending until the quasi-experimental research study is completed. Discussion Volatile inhalational anesthetics account for twenty percent of pharmacy costs in the anesthesia department.10,16 By using a pharmacoeconomic model, it can be seen that careful choice of anesthetic for patients can represent a large cost containment for the anesthesia department in the hospital, without compromising patient care. All patients need to be considered a new case and may not fit into the pharmacoeconomic model because of family histories (e.g. malignant hyperthermia). However, when possible, using Sevoflurane for the choice inhalation anesthetic for general surgery cases rather than Desflurane for those lasting less than one hour can result in large cost savings for the anesthesia department. Over twenty thousand dollars could be saved if the Southwestern Pennsylvania hospital would utilize Sevoflurane over Desflurane for two-thirds of their total surgeries requiring general anesthesia for less than one hour. It is important to mention that as a professional anesthesia student, FGF commonly observed with Sevoflurane are 2 LPM and FGF with Desflurane commonly observed are 2 LPM. The nephrogenicity associated with Sevoflurane is not commonly observed when this amount of FGFs are used.7 With the use of 1 LPM FGF when using Desflurane, as there is no minimum FGF required to avoid physiological aberrance, 17,19 there is also a great cost savings maintained for the anesthesia department. Limitations There are limitations in any study when research is conducted and from this study, results are limited to a single institution and this limits its external validity as a result. Randomization was not included in this research study as a convenience sample population was used at one hospital location. The study was not extremely descriptive as patients with higher PS scores were not studied in this particular research project. This study is also missing research on older age groups, as participants age twenty to forty were included only. As all of these limitations can be seen in the experimental study, the results from this research study cannot be imposed on larger populations and therefore generalizability is poor. Future research can make these findings representable and provide for better generalization. Future Recommendations for Research In future research, randomization should be used when developing research as this will strengthen the results. Larger sample populations should be used in defined, smaller age variances to be able to impose the results on a specific group of patients. Defined surgeries should be used in sample populations to show stronger significance when looking at varied surgical procedures their results. With the inclusion of the above criteria, the research study would be experimental rather than quasi-experimental, and results could be superimposed onto given populations with much stronger data observance. Dissemination This research project will appear in the May, 2013 edition of Anesthesia and Analgesia in its entirety with all results included. There will also be one hour lectures provided on these research findings at the University of Pittsburgh at Greensburg, Robert Morris University, and St. Vincent College, times and final adjusted locations are to be announced via bulletins, which be hung in the cafeterias of each of these locations. Conclusion Inhalational anesthetics represent a significant cost for pharmaceutical costs in the anesthesia department. It is important for professional anesthesia providers to deliver cost-effective, safe anesthesia care to patients in surgery. When analyzing surgical procedures requiring general anesthesia for less than one hour, the use of Sevoflurane rather than Desflurane as the choice inhalation anesthetic in surgery can provide the anesthesia department an avenue of cost savings without compromising patient care. When Desflurane must be used for patients who cannot be administered Sevoflurane, it is important to keep in mind there is no recommendation for FGF rates, and cost savings can also be preserved by utilizing low FGFs when using Desflurane. References Weinberg L, Story D, Nam J, McNicol L. (2010). Pharmacoeconomics of volatile inhalational anaesthetic agents: an 11-year retrospective analysis. Anaesthesia and Intensive Care, 38(5), 849-854. Lockwood GC White DC (2001). Measuring the costs of inhaled anesthetics. British Journal of Anesthesia, 87(4), 559-563. Odin I, Feiss P. (2005). Low flow and economics of inhalational anaesthesia. Best Practice Research Clinical Anaesthesiology, 19(3), 399-413. Strum EM, Szenohradszki J, Kaufman W, Anthone GJ, Manz IL, Lumb PD (2004). Emergence and Recovery Characteristics of Desflurane Versus Sevoflurane in Morbidly Obese Adult Surgical Patients: A Prospective, Randomized Study. Anesthesia and Analgesia, 99, 1848-1853. Boldt J, Suttner S. (2000). Low-Flow Anesthesia: Does it have Potential Pharmacoeconomic Consequences? Pharmacoeconomics, 17(6), 585-590. Golembiewski J. (2010). Economic Considerations In the Use of Inhaled Anesthetic Agents. American Journal of Health-System Pharmacy, 67(4), 9-12. Meyer T. (2010). Managing inhaled anesthesia: Challenges from a health-system pharmacists perspective. American Journal of Health-System Pharmacy, 67(4), 4-8. Boldt J, Juan N, Kumle B, Heck M, Mund K. (1998). Economic Considerations of the Use of New Anesthetics: A comparison of Propofol, Sevoflurane, Desflurane, and Isoflurane. Anesthesia and Analgesia, 86, 504-509. Agoliati A, Dexter F, Lok J, et al. (2010). Meta-Analysis of Average and Variability of Time to Extubation Comparing Isoflurane with Desflurane or Isoflurane with Sevoflurane. Anesthesia and Analgesia, 110(5), 1433-1439. Dolk A, Cannerfelt R, Anderson RE, Jakobsson JP. (2002). Inhalation anesthesia is cost-effective for ambulatory surgery: a clinical comparison with propofol during elective knee arthroscopy. European Journal of Anesthesiology, 19(2), 88-92. Chernin EL (2004). Pharmacoeconomics of inhaled anesthetic agents: Considerations for the pharmacist. American Journal of Health-System Pharmacy, 61(4), 18-22. Beaussier M, Deriaz H, Abdelahim Z. (1998). Comparative effects of desflurane and isoflurane on recovery after long lasting anaesthesia. Canadian Journal of Anaesthesia, 45(5), 429-434. White PF. (2010). Facilitating Recovery from Anesthesia: Assessing the Costs and Benefits of Anesthetic Drugs. Anesthesia and Analgesia, 110(2), 273-275. Gupta A, Stierer T, Zuckerman R, Sakima N, Parker S, Fleisher LA (2004). Comparison of Recovery Profile After Ambulatory Anesthesia with Propofol, Isoflurane, Sevoflurane and Desflurane: A Systematic Review. Anesthesia and Analgesia, 98, 632-641. Traynor K. (2009). Inhaled anesthetics present cost-saving opportunity. American Journal of Health-System Pharmacy, 66(7), 606-607. Kapur P. (1994). Pharmacy Acquisition Costs: Responsible Choices Versus Overutilization of Costly Pharmaceuticals. Anesthesia and Analgesia, 78, 617-618. Dexter F, Bayman EO, Epstein RH (2010). Statistical Modeling of Average and Variability of Time to Extubation for Meta-Analysis Comparing Desflurane to Sevoflurane. Anesthesia and Analgesia, 110(2), 570-580. Southwestern Pennsylvania Hospital. (2012). Annual Anesthesia Data Tracking Information. Accessed 08/30/2012 with Permission from Corporate Department. Southwestern Pennsylvania Hospital. (2012). Pharmacy Records. Accessed 08/30/2012 with Permission from Corporate Department. Appendix A Table 1: Cost of Inhalational Anesthetic per a Southwestern Pennsylvania Hospital Pharmacy Records Inhalational Anesthetic Cost Per Bottle ($) Total Volume in Bottle (mL) Cost per mL of Liquid ($) Sevoflurane (Ultane) 100.82 250 0.40 Isoflurane (Forane) 9.73 100 0.09 Desflurane (Suprane) 136.37 240 0.56 Reference 19. Table 3: Calculated MAC Hour Inhalation Anesthetic Cost at a Southwestern Pennsylvania Hospital FGF Rate (L/Min) Isoflurane ($) Desflurane ($) Sevoflurane ($) 1 0.31 9.68 2.71 2 0.62 19.36 5.43 3 0.93 29.04 8.14 All estimated costs are based on duration of 60 minutes and the formula proposed by Golembiewski. Isoflurane calculations are based on concentration of 1.15%, MW of 184g, cost per mL=$0.09 and D of 1.49 g/mL Desflurane calculations are based on concentration of 6%, MW of 168g, cost per mL=$0.56, and D of 1.45g/mL Sevoflurane calculations are based on concentration of 2.0%, MW of 201g, cost per mL=$0.40, and D of 1.51g/mL Appendix B Chart 1: Total Anesthesia Cases in July, 2012: Time Intervals from a Southwestern Pennsylvania Hospital Reference 18. Table 2: Estimated Cost per MAC Hour ($) of Inhaled Anesthetic Gases: Based on FGF Rates FGF Rate (L/Min) Isoflurane ($) Desflurane ($) Sevoflurane ($) 1 0.5 12.9 6.0 2 1.0 25.9 12.1 3 1.5 38.8 18.1 All estimated costs are based on duration of 60 minutes and the formula proposed by Golembiewski. Isoflurane calculations are based on concentration of 1.15%, MW of 184g, cost per mL=$0.15 and D of 1.49 g/mL Desflurane calculations are based on concentration of 6%, MW of 168g, cost per mL=$0.96, and D of 1.45g/mL Sevoflurane calculations are based on concentration of 2.0%, MW of 201g, cost per mL=$0.90, and D of 1.51g/mL Reference 7. Appendix C Chart 2: Number of Bottles of Inhalational Anesthetic Used Annually at a Southwestern Pennsylvania Hospital Reference 19. Chart 3: Annual Expenditure on Inhalational Anesthetics at a Southwestern Pennsylvania Hospital
Saturday, October 12, 2019
Immanuel, Kant (1724-1804) Essay examples -- essays research papers
Immanuel Kant was born in 1724 in the East Prussian town of KÃ ¶nigsberg and lived there practically all his life. He came from a deeply pious Lutheran family, and his own religious convictions formed a significant background to his philosophy. Like Berkeley, he felt it was essential to preserve the foundations of Christian belief. Kant became Professor of Logic and Metaphysics at the University of KÃ ¶nigsberg in 1770 and taught there for most of his life. He was also greatly interested in science and published works on astronomy and geophysics. His three most significant works were published later in life. The Critique of Pure Reason came out in 1781, followed in 1788 by the Critique of Practical Reason and in 1790 by the Critique of Judgment. The Critique of Pure Reason is one of the most important works in the whole of philosophy. Unfortunately it is also one of the most unreadable - Kant himself described it as dry and obscure. Kant had generally been an outgoing and friendly man but towards the end of his life his mental faculties and his sight deteriorated badly. He died a shadow of his former self, aged 80. One of his most quoted sayings is carved on his gravestone in KÃ ¶nigsberg: "Two things fill my mind with ever-increasing wonder and awe, the more often and the more intensely the reflection dwells on them: the starry heavens above me and the moral law within me". IDEAS Kant believed that there are clear limits to what we can know. You could perhaps say that the mind's "glasses" set these limits. The philosophers before Kant had discussed the really "big" questions - for instance, whether man has an immortal soul, whether there is a God, whether nature consists of tiny indivisible particles, and whether the universe is finite or infinite. Kant believed there was no certain knowledge to be obtained on these questions. In such great philosophical questions, he thought that reason operates beyond the limits of what we humans can comprehend. At the same time there is in our nature a basic desire to pose these questions. When, for example, we ask whether the universe has always existed, we are asking about a totality of which we ourselves are a tiny part. We can therefore never completely know this totality. According to Kant there are two elements that contribute to our knowledge of the world - sensory perception and re... ...etimes you might only be kind and helpful to others because you know it pays off. It could be a way of becoming popular. But if this is your only motive you are not acting out of respect for moral law. You might be acting in accordance with moral law - and that could be fair enough - but if it is to be a moral action, you must have conquered yourself. Only when you do something purely out of duty can it be called a moral action. Kant's ethics is therefore sometimes called duty ethics. Kant also advocated the establishment of a "league of nations". In his treatise Perpetual Peace, he wrote that all countries should unite in order to assure peaceful coexistence between nations. He believed that man's "practical reason" would force the nations to emerge from the wild state of nature which creates wars, and make a contract to keep the peace. Kant recognised that this would take time to achieve but he saw it as our duty to work for the universal and lasting securing of peace. About 125 years after the appearance of Kant's treatise in 1795, the League of Nations was founded, after the First World War. After the Second World War it was replaced by the United Nations.
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